Abstract Background Mucolipidosis type IV (MLIV) is an autosomal recessive lysosomal storage disorder characterized by severe neurologic and ophthalmologic abnormalities.Recently the MLIV gene, MCOLN1, has been identified as a new member of the transient receptor potential (TRP) cation channel superfamily.Here we report the cloning and characteriza
In order to improve the safety of the braking process of high-speed train, the brake disc heat dissipation structure needs to Heel Support be optimized.The ANSYS-workbench software was used to establish a three-dimensional transient model.The temperature field simulation was performed on the brake discs with 8 different structural parameters based
Previous studies demonstrated that critically shortened telomere lengths correlate with the chromosome instability in carcinogenesis.However, little has been noticed regarding the correlation of long telomeres at specific chromosomes with malignant disorders.We studied relative telomere lengths (RTLs) for individual chromosomes using the quantitati
Printed Electronics (PE) based on additive manufacturing has a rapidly growing market.Due to large feature sizes and reduced complexity of PE applications compared to silicon counterparts, they are more prone to counterfeiting.Common solutions to detect counterfeiting insert watermarks or extract unique fingerprints based on (irreproducible) proces
Introduction: The importance of Vitamin E scientific research in prevention of drug addiction is obvious.The main site of drug action is the brain.Mu receptor is the first place of drug action.In this study, the rate of mu receptor gene single nucleotide polymorphism (SNP) was compared in addicts and non-addicts.Methods: In this study AA, AG and AA